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publicationDate 2022-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-4086342-A1
titleOfInvention Modified immune effector cell and preparation method therefor
abstract Provided is a modified immune effector cell, wherein compared with the expression and/or activity of the corresponding gene in a corresponding unmodified cell, the expression and/or activity of the TRAC gene and the HLA-A gene are down-regulated, the expression and/or activity of the B2M gene is not down-regulated, and the expression and/or activity of the CIITA gene is not down-regulated. Also provided is a method for preparing the modified immune effector cell.
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