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filingDate 2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74b094d5a2d0df804f1a074b281283f7
publicationDate 2022-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-4081256-A1
titleOfInvention Upar-targeted photothermal optical probes for photothermal therapy
abstract The present invention relates to tumor-targeted probes for use as medicaments and for use in treatment of cancer and to methods of treatment wherein such probes are used. The probes consist of a light-absorbing molecule linked directly or via a spacer to a peptide targeting the urokinase-type plasminogen activator receptor (uPAR). When irradiating the light-absorbing molecule of the probe with laser beams from an external source heat will be released locally to tumor cells expressing uPAR resulting in tumor ablation.
priorityDate 2019-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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