| abstract |
The present invention refers to the method of preparing genetically modified poultry resistant to subgroup J avian leukosis virus, which is characterised by the fact that this poultry carries the W38 deletion introduced into the chNHE1 gene using CRISPR/Cas9-mediated homologous recombination, or optionally, carries the W38 deletion introduced using CRISPR/Cas9 and a specific sgRNA, to yield domestic chicken or domestic turkey resistant to subgroup J avian leukosis virus (ALV). |