http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4074839-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f2a9661a1ae34281bd90af0a6067a9e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6823 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6823 |
| filingDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2b0da648229e5638110c1cf65514bce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e846a277bf88bf46e59936b0c2d3278b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f41b909d8d89919c7b142182b7cdc49 |
| publicationDate | 2022-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-4074839-A1 |
| titleOfInvention | Optimized oligonucleotide tx probe for a multiplexing analysis of nucleic acids and a multiplexing method |
| abstract | The present invention provides a, preferably fully automated and/or multiplex, method for the simultaneous detection of a plurality of molecular genetic analytes in a collective and continuous reaction set up and at least one analyte specific oligonucleotide TX probes with a cleavable hydrolysis product for use in said method. Through the method the plurality of cleavable hydrolysis products is specifically released by a nuclease from the respective TX probes. Following a separation step, preferably in a capillary electrophoresis, for each hydrolysis product a clear and distinguishable from others signal is achieved. Each separated hydrolysis product respectively results in a signal enabling the qualitative and/or quantitative detection of each analyte comprising a molecular variant, e.g. single nucleotide polymorphism (SNP), deletion-insertion polymorphism (DIP) or other, respectively, that was targeted specifically by the plurality of TX probes. Preferably, the method is suitable to detect qualitatively and/or quantitatively small molecular variants as such SNP. |
| priorityDate | 2021-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.