http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4071160-A1

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filingDate 2022-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-4071160-A1
titleOfInvention Process for the preparation of cortexolone 17 a-propionate and new hydrated crystalline form thereof
abstract The present invention is directed to a process for the preparation of cortexolone 17α-propionate, comprising a hydrolysis reaction of an ortho-ester of formula (III)n nin which R is a hydrogen atom or a methyl group, nin the presence of a dilute solution of acetic acid. n The present invention is also directed to a hydrated crystalline form of cortexolone 17a-propionate obtained by such process.
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priorityDate 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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