http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4069308-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24be4f32161f092b0ed9ef188c758684 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-595 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G73-028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0034 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-59 |
| filingDate | 2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25a43ef2017567f9a5d8ae96e8fbbba3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6af4bc287cbd07c77fd4cdf6f816fb59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57ca8606702a059655394eec80a14918 |
| publicationDate | 2022-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-4069308-A2 |
| titleOfInvention | Dendrimer compositions and methods for drug delivery to the eye |
| abstract | Dendrimer compositions and methods for the treatment of one or more inflammatory and/or angiogenic diseases and/or disorders of the eye include hydroxyl-terminated dendrimers complexed or conjugated with one or more active agents for the treatment or alleviation of one or more symptoms of the diseases of the eye, and/or for diagnosing the diseases and/or disorders of the eye. The dendrimers may include one or more ethylene diamine-core poly(amidoamine) (PAMAM) hydroxyl-terminated generation-4, 5, 6, 7, 8, 9, or 10 dendrimers. The active agents may be VEGFR tyrosine kinase inhibitors including sunitinib or analogues thereof. Preferably, the compositions are suitable for administration via a systemic route to target activated microglia/macrophages in retina/choroid. |
| priorityDate | 2019-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 329.