| abstract |
Methods of, inter alia, detecting the presence, absence, amount, of change of one or more analytes, such as one or more genetic variants, including allelic variants, in one or more query samples include providing one or more sensors that each include capture nucleic acids disposed on a functionalized surface of one or more giant magnetoresistance (GMR) sensors. Exemplary modes of operation include, inter alia, removing or adding magnetic particles from the vicinity of sensor surfaces by interactions with the capture nucleic acids. The methods feature, inter alia, detecting the presence of one or more analytes in one or more query samples by measuring magnetoresistance change of the one or more GMR sensors based on determining magnetoresistance before and after passing magnetic particles over the one or more sensors. |