http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4028504-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c37ea6c0ccf659261758e2450ac848e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2523-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2531-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0696 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9acd8a51e4747f45ed59ceb96e0a9a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1af80a57613a846486337afa72029b2 |
| publicationDate | 2022-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-4028504-A1 |
| titleOfInvention | End-to-end platform for human pluripotent stem cell manufacturing |
| abstract | A closed, automated and scalable stirred tank bioreactor platform, capable of sustaining high fold expansion of hPSCs is provided. hPSCs are expanded in a controlled bioreactor using perfused xeno-free media. Cell harvest and concentration are performed in closed steps. The hPSCs can be cryopreserved to generate a bank of cells or further processed as needed. Cryopreserved cells can be thawed into a 2D tissue culture platform or a 3D bioreactor to initiate a new expansion phase or be differentiated to the clinically relevant cell type. The expanded hPSCs express hPSC-specific markers, have a normal karyotype and the ability to differentiate to the cells of the three germ layers. This end-to-end platform allows large expansion of high quality hPSCs that can support the required cell demand for various clinical indications. |
| priorityDate | 2019-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 107.