| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca9efe8d18d141154d8ea015903e36c0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0375
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6489
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6491 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2020-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1592bcc765158f5e8065eecce867ef63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_518b75624d279ad3d61fe4daaab16c85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37ada91d492aeb4b278e79a057522947
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d70f78212b946d77feeb388c579a6fd8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03323b08cb76dcfd681d2ffee8c331f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acd038255720ac0b0e090acf33a833c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d84805da5f22cc2292f58c424745709d |
| publicationDate |
2022-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-4019545-A1 |
| titleOfInvention |
Immunogenic peptide fragment of metalloproteinase adamts-7 and application thereof in resisting against atherosclerosis and related diseases |
| abstract |
The present invention discloses immunogenic peptide fragments of metalloprotease ADAMTS-7 and uses thereof in anti-atherosclerosis and related diseases. The present invention discloses a short peptide first, which is any one of the followings: a short peptide having the amino acid sequence shown in SEQ ID NO: 1 in the sequence listing; a short peptide having the amino acid sequence shown in SEQ ID NO: 2 in the sequence listing; a short peptide having the amino acid sequence shown in SEQ ID NO: 3 in the sequence listing; a short peptide having the amino acid sequence shown in SEQ ID NO: 4 in the sequence listing. The present invention further discloses uses of conjugates containing the above short peptides and vaccines containing the conjugates. The vaccines containing the short peptides of the present invention can remarkably inhibit the intimal neogenesis in the vascular restenosis mouse models and the occurrence of atherosclerosis in high-fat-fed mice, and can be used for the prevention or treatment of atherosclerosis and/or vascular restenosis. |
| priorityDate |
2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |