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filingDate 2020-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca1c2a56c5719309ef8ae63df76aa51f
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publicationDate 2022-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-4013857-A1
titleOfInvention Immunoresponsive cells armoured with spatiotemporally restricted activity of cytokines of the il-1 superfamily
abstract Provided herein are immunoresponsive cells having IL-1 superfamily activities with spatiotemporal restriction. The immunoresponsive cells can further express a protease for regulating the IL-1 superfamily activities, and a chimeric antigen receptor (CAR) or a parallel CAR. Also provided herein are methods of preparing the immunoresponsive cells and methods of directing T cell mediated immune response using the immunoresponsive cells.
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type http://data.epo.org/linked-data/def/patent/Publication

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