http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4008338-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb351a5a4e03ee3773bd0df5dbae9ac3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1825 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
filingDate | 2020-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06da3e316c25bd9b05f75e9daae54d1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f3c4b355b8db07bc72d580174bd7006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d20afe4a1c0eafa9b597b8ae8a77783 |
publicationDate | 2022-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-4008338-A1 |
titleOfInvention | Use of fgf21 in preparation of medicine for treating colorectal cancer |
abstract | The present invention discloses application of FGF21 in the preparation of medicines for treating colorectal cancer, and belongs to the technical field of medicine. The FGF21 protein provided by the present invention is a secreted protein composed of about 210 amino acids. The present invention found that FGF21 has the effect of treating colorectal tumors for the first time. It is proved by cytology and animal experiments that FGF21 can inhibit the proliferation, invasion and migration of colorectal tumor cell lines; can significantly reduce the size of tumor lesions in mouse models. The medicines prepared from FGF21 as the active ingredient for treating colorectal cancer has good safety and long duration of drug action, while it protects organs from damage and has the effect of improving lipid metabolism disorders. |
priorityDate | 2020-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 392.