| abstract |
Provided herein belongs to the field of pharmaceuticals, and specifically relates to a Teixobactin analogue and use thereof. It further relates to a pharmaceutical composition comprising the compound and use of the compound and the pharmaceutical composition thereof in inhibiting the growth and /or reproduction of Gram-positive bacteria or Mycobacterium tuberculosis. It also provides a compound having Formula (Ia) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof. |