| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce4a285d9d49302c4b2627f5286ffd2e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3895
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3826
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 |
| filingDate |
2020-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc46ea20cf641f01a21863992eb075ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_557f6543166e9e426eaec0e3cd365ce0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42e82a6fd248a2d4acbd9fac91be66bb |
| publicationDate |
2022-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3988138-A1 |
| titleOfInvention |
Multilayer engineered heart muscle |
| abstract |
The application describes a method for manufacturing a multilayer engineered heart muscle. Specifically, the method relates to (i) providing a liquid reconstitution mixture in a mould and (ii) culturing said mixture. The method is characterized by a sequential addition of one or more further liquid reconstitution mixtures in order to obtain a multilayer engineered heart muscle. Said muscle ideally has the form of a patch, a pouch, or a cylinder. Furthermore, the application relates to a multilayer engineered heart muscle comprising collagen, cardiac myocytes and non-myocytes originating from at least 2 layers. Said multilayer engineered heart muscle forms the basis for several in vitro and in vivo applications such as the production of a multilayer engineered heart muscle for use in a patient, for example for use in heart repair. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022157197-A1 |
| priorityDate |
2020-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |