| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_536f001e42b4421737473b6644539991 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56983 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
| filingDate |
2020-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc94d598839a40c0e27671372251b02f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb26b057749a4475bfa0fe2ed7f9ecbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86a15bf22cbf5c021b48317f1d235401
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_090a9d6ebd725bd21b8ad5f2456a9c53 |
| publicationDate |
2022-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3983429-A1 |
| titleOfInvention |
Amino acid sequences of recombinant flaviviral proteins and recombinant flaviviral virus-like particles, their medical use in the prevention of zika virus infection and for in vitro diagnosis |
| abstract |
The invention relates to the amino acid sequences of individual recombinant Zika virus proteins or recombinant virus-like particles comprising at least two fragments of Zika virus proteins. In both types of sequence, the E structural protein or only the cytoplasmic domain of E protein and / or the prM structural protein were used. Moreover, in some sequences, the fragment of tick-borne encephalitis virus E protein was used. The invention in the form of amino acid sequences of recombinant proteins or recombinant virus-like particles has a potential therapeutic use to prevent Zika virus infection as an immunogenic component for the preparation of vaccines. The invention in the form of recombinant proteins or recombinant virus-like particles with amino acid sequences according to the invention can be used as an in vitro diagnostic antigen for the detection of flavivirus infections, in particular Zika virus, tick-borne encephalitis virus and Dengue virus as a component of diagnostic tests. |
| priorityDate |
2019-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |