| abstract |
Disclosed are a compound as shown by the following formula 1, and a pharmaceutically acceptable salt, an ester, a hydrate and an organic solvate thereof. In the formula (1), the groups R<sub>1</sub> to R<sub>17</sub> are independently selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, C<sub>1</sub>-C<sub>8</sub> alkyl, C<sub>1</sub>-C<sub>8</sub> alkoxy, carbonyl, hydroxyl, amino, azido, carboxyl and C<sub>1</sub>-C<sub>8</sub> alkylsulfinyl, respectively; and X is a carbon or nitrogen atom; Y is selected from the following groups: a single bond, C<sub>1</sub>-C<sub>8</sub> alkylene, C<sub>6</sub>-C<sub>20</sub> arylene and C<sub>4</sub>-C<sub>20</sub> heteroarylene; and n is an integer from 5 to 20. Also provided in the present invention are a pharmaceutical composition containing the compound, and use thereof in the field of tumor therapy. |