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publicationDate 2022-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3977075-A1
titleOfInvention Celiac disease diagnosis method
abstract A diagnosis method for detecting celiac disease comprising the following steps: a) performing a Raman spectroscopy of a blood serum sample; b) selecting from the Raman spectrum a first characteristic band of a first indicator of celiac disease, a second characteristic band of a second indicator of celiac disease, and a third characteristic band of a third indicator of celiac disease; c) performing a deconvolution of at least the second band and the third band of the Raman spectrum, obtaining a respective plurality of Gaussians; d) calculating a first sum A2 of the areas of the Gaussians related to the second band, and a second sum A3 of the areas of the Gaussians related to the third band; e) calculating a first ratio A2/A1 and a second ratio A3/A1, wherein A1 is the area under the first band; f) verifying that the first ratio A2/A1 is greater than a first threshold value and that the second ratio A3/A1 is greater than a second threshold value to confirm the celiac disease diagnosis.
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