Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c666474ffc0184da7e8aafe5f0b324d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-20 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B50-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate |
2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baa318559bb99bb582620b28bf14804b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9915dfbad2c08d3a01e2f1b3094ea69 |
publicationDate |
2022-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3976829-A1 |
titleOfInvention |
A method of treatment or prophylaxis |
abstract |
Disclosed herein are methods for treating complex disorders in human subjects and for preventing complex disorders in human subjects at risk of developing the disorder, comprising identifying one or more pharmacologically relevant biological pathways associated with a complex disorder and selecting an agent suitable for the treatment or prevention of the complex disorder. As described herein, the quantification of common variant enrichment in biological pathways with known drug targets provides a means of functionally annotating genome-wide polygenic risk scoring, which provides an indication of an individual's exposure to risk variants that are potentially treatable using existing pharmaceutical agents, dietary supplements or lifestyle interventions. |
priorityDate |
2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |