| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43fe117d5e377852bbddf9b05a6702ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2021cafa8df7b0dec20ae2c7682f639 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0491
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H5-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 |
| filingDate |
2020-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cea1b1171ff0c35216b54474e20cbe56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c31c2c294e7155bb87d09477a937603f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e900c7aff10dbd3c37398690ed092429
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6c8d539c581010820a33ac366d4d761
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9cc81fa76a08fc7411715a045dd1f25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7216e9e07c828039dc3b05feb0ac13ae |
| publicationDate |
2022-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3976118-A1 |
| titleOfInvention |
18f-labeled novel tetrazines imaging probes for pretargeting in pet imaging |
| abstract |
Novel 18F-labelled tetrazines are provided which are highly reactive to be effective in vivo, suitable for pretargeted positron emission tomography (PET) and accessible in radiochemical yields (RCYs) which allow access to 18F-labeled tetrazines for clinical applications. The 18F-labelled tetrazines are developed using a Cu-mediated click indirect labelling approach. Only a subset of compounds appeared to be suitable for clinical pretargeted imaging strategies, and a particular compound which includes the use of an 18F-labelled azide synthon having an azide structure with glucose as the linker and a triazole moiety within the linker, appears to be highly suited for clinical pretargeted imaging purposes. |
| priorityDate |
2019-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |