abstract |
The present invention provides a method including the step of adding a halogen donor such as N-iodosuccinimide, potassium iodide (KI), iodine (I 2 ), N-bromosuccinimide, N-chlorosuccinimide and N-fluorobenzene-sulfonimide to halogenate benzoic acid containing a nitro group in order to prepare an indole or indazole compound containing a nitro group which is an intermediate structure necessary for synthesizing a pharmaceutically useful indole or indazole compound. |