http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3956467-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1075 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate | 2020-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd12b1b447da3361094f3faabb3d5b47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_146e401bf7690f57ad8b7ba9b39f56de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b81d2805c1b56707e23612e0b930b8e |
| publicationDate | 2022-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3956467-A1 |
| titleOfInvention | Small molecule screening cellular assay using modified beads |
| abstract | A method for screening a DNA-encoded library of chemical structures (2) for activity in a cellular target (11) wherein the chemical structures (2) of the library, the corresponding encoding DNA (4) and, optionally, a chemical probe (7/8/9) susceptible to the response molecule (12) are covalently linked to beads (1); the method comprising providing an incubation medium (13) or aliquot thereof comprising the cellular target (11) and exactly one or more than one bead (1) as defined above, releasing the chemical structures (2) from the bead(s) (1) in the incubation medium (13) or aliquots thereof by cleaving the structure linkers (3) and incubating the released chemical structures (2) and the cellular target (11); and sequencing the encoding DNA present or remaining on the bead(s) (1). A bead (1) suited for the method is also provided. |
| priorityDate | 2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.