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filingDate 2019-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3950007-A1
titleOfInvention Method for preparing nano diagnostic agent capable of selective staining of inflammatory abnormal tissues or tumor tissues
abstract The present invention relates to a method for preparing a nano diagnostic agent capable of selective staining of abnormal inflammatory tissues or tumor tissues. The method for preparing a nano diagnostic agent, according to the present invention, is characterized by comprising: a step of forming a first mixture by mixing polysorbate 80, soybean oil, and a water-insoluble staining material; a step of forming a second mixture by mixing and then heating the first mixture and a triblock copolymer; a step of forming a nano platform solid by cooling the second mixture; a step of forming a third mixture by mixing a solvent with the nano platform solid; a step of removing impurities from the third mixture; and a step of forming a nano-composite by freeze-drying the third mixture from which the impurities are removed. Thereby, the present invention can increase the search efficiency of a disease lesion by being transmitted through micropores of a tumor through direct permeation and absorption so as to precisely distinguish normal tissues from abnormal tissues.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3977910-A4
priorityDate 2019-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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