abstract |
The present invention generally relates to a therapeutic hydrogel device. Particularly, the present invention discloses a planar hybrid hydrogel macrodevice includes an array of microwells and a therapeutic microtissue within each of a plurality of the microwells, and the microwells further include a peg arranged to guide the formation of a toroid-shaped microtissue. More particularly, the present invention discloses a composition for implantation, and the composition has a plurality of biocompatible hydrogel-based microcapsules each having a toroid-shaped microtissue encapsulated therein, of which the microtissue secretes a therapeutically effective substance. |