Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07bb09c3c02a70c2bfea121aab7ba7ec |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-20 |
filingDate |
2020-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_563eab4329d172b3dd292edfa86ecdb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62af8f6a03a287ecafe70f49c94df0cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0395cc399cb913321e9e75542c025c67 |
publicationDate |
2022-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3940705-A1 |
titleOfInvention |
Method for prediction of the silencing efficiency of guides targeting a gene of interest |
abstract |
The present invention relates to a method for prediction of the targeting efficiency of guides targeting a gene of interest, said guides locating a target in a gene sequence, by evaluating of data provided by screens providing values of targeting characteristics of guides, characterized by the steps of na) Selecting a set of guides along with gene intrinsic features related to a gene of interest and guide features; nb) Inputting the selected features into an automated machine learning algorithm and nc) Calculating an estimate of targeting efficiency of said selected guides by use of the automated machine learning algorithm. |
priorityDate |
2020-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |