| abstract |
Disclosed herein are left atrial appendage (LAA) occluders that include self- powered physiological sensors to monitor physiological parameters of a subject. The sensors can be powered by harvesting energy generated by the patient's body or using wireless power delivery technologies. The disclosed devices can be used to close the LAA and to provide self-powering sensors to wirelessly monitor physiological parameters such as heart rate, pressure, temperature, size of the atrium, and levels of biomarkers such as C-reactive protein (CRP) and B-type natriuretic peptide (BNP) (e.g., using biosensors). In addition to addressing the stroke risk for patients with non-valvular atrial fibrillation, the disclosed devices offer post-surgical connected care that can reduce hospital re admissions, provide superior medical management, and improve patient quality of life. |