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filingDate 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_459373c3600eae6e3c418a8a935d8bc3
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publicationDate 2022-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3930733-A1
titleOfInvention Methods of modulating cd160 function in the antigen-specific immune cell and uses thereof
abstract The present invention provides modified antigen-specific immune cells expressing an exogenous CD 160 protein. In some embodiments, the modified antigen-specific immune cell further comprises a functional exogenous receptor, such as an engineered TCR or a CAR. The present invention also provides methods of modulating CD 160 activity in antigen-specific immune cells. The present invention also provides methods and pharmaceutical compositions for cancer treatment using the modified antigen-specific immune cells and the modulators of CD 160 activity described herein.
priorityDate 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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