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filingDate 2020-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3927363-A1
titleOfInvention Recombinant antimicrobial multidomain polypeptide, methods of producing and uses thereof
abstract A novel recombinant antimicrobial multidomain polypeptide in an aggregated and functional format is provided. The antimicrobial multidomain polypeptide comprises at least three peptidic domains: a) a non-enzymatic antimicrobial peptidic domain from mammal's immune system, b) a bacterial binding peptidic domain which interacts with the bacterial cell wall or membrane, and c) an enzymatic antimicrobial peptidic domain from mammal's immune system. The antimicrobial multidomain polypeptide exhibits a broad-spectrum antimicrobial effect and is produced in an efficient production system, i.e in form of inclusion bodies.
priorityDate 2019-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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