http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3925951-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f8fe90bd741939b669967410a817918 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D225-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D225-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D225-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54 |
filingDate | 2015-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ed9ac967d4802e4ade2ed9ae467c70e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_440c25f6b47af7b037830f0c7d182a87 |
publicationDate | 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-3925951-A1 |
titleOfInvention | Process for the cycloaddition of a(hetero)aryl 1,3-dipole compound with a (hetero)cycloalkyne |
abstract | The present invention relates to a process comprising the step of reacting a (hetero)aryl 1,3-dipole compound with a (hetero)cycloalkyne, wherein:a (hetero)aryl 1,3-dipole compound is defined as a compound comprising a 1,3-dipole functional group, wherein the 1,3-dipole functional group is bonded to a (hetero)aryl group, and wherein the (hetero)aryl 1,3-dipole compound is a (hetero)aryl azide or a (hetero)aryl diazo compound;wherein:(i) the (hetero)aryl group of the (hetero)aryl 1,3-dipole compound comprises one or more substituents having a positive value for the para-Hammett substituent constant σ<sub>p</sub> and/or the meta-Hammett substituent constant σ<sub>m</sub>, and/or(ii) the (hetero)aryl group of the (hetero)aryl 1,3-dipole compound is an electron-poor (hetero)aryl group, wherein an electron-poor (hetero)aryl group is:(ii-a) a (hetero)aryl group wherein the (hetero)aromatic ring system is bearing a positive charge, and/or(ii-b) a (hetero)aryl group wherein the ratio {number of π-electrons present in the (hetero)aromatic ring system} : {number of protons present in the nuclei of the (hetero)aromatic ring system} is lower than 0.167 for a 6-membered ring, or lower than 0.200 for a 5-membered ring;and wherein the (hetero)cycloalkyne is a (hetero)cyclooctyne or a (hetero)cyclononyne according to Formula (1):The invention also relates to the products obtainable by the process according to the invention. |
priorityDate | 2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 506.