Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 |
filingDate |
2020-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c13265e742b6076d0615e3db0de114d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21fff73c07f3f3c76aaad01600b26c8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dce469a6dad9ae9c17eecd6c7ec1bca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_010f14120e0eadb5f7897b70ff035180 |
publicationDate |
2021-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3921409-A1 |
titleOfInvention |
Genetically modified hematopoietic stem and progenitor cells (hspcs) and mesenchymal cells as a platform to reduce or prevent metastasis, treat autoimmune and inflammatory disorders, and rebalance the immune milieu and dysregulated niches |
abstract |
Provided are compositions comprising genetically modified hematopoietic stem and progenitor cells (HSPCs) and/or genetically modified mesenchymal cells, wherein the cells contain a vector comprising a transgene, as well as methods of producing the genetically modified HSPCs and genetically modified mesenchymal cells, and methods of treating or preventing cancer (e.g., metastasis) and neurodegenerative conditions, autoimmune disorders, and inflammatory disorders. |
priorityDate |
2019-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |