abstract |
The present invention relates to a pharmaceutical composition comprising as active ingredients a compound represented by general Formula I:n n including any pharmaceutically acceptable salt, hydrate, solvate, enantiomer and diastereomer thereof, and any mixtures thereof, nwherein: nX and R are as herein defined and nat least one ingredient selected from the group consisting of a prostaglandin analog, a β-blocker, an adrenergic agent, an α2-adrenergic receptor agonist, a miotic agent, a carbonic anhydrase inhibitor and a cholinergic agonist, and na pharmaceutically acceptable carrier. |