| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dc5714e99888c09333c669545a6bd0e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5383
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-252
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 |
| filingDate |
2020-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdb1153dff2b59e88cf700c4eff88c58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5260456356295f540f7db4c9f875ce51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6155d164bed83b9691a06b1f0a77212e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52a7b3d66298b0d567e10b25e59bacaf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef319a783324f14602548bdf48f8fd9f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37970dfd727fe487d79b82884b0aaeab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56a7c78d125df44763645eede8c6cb6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab30fb582ccf1ccd9c22b0dc9b34db9c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b82d87e49975be73955e13a2e007b79 |
| publicationDate |
2021-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3907223-A1 |
| titleOfInvention |
Method for preparing drug toxin pnu-159682 of antibody drug conjugate, and intermediate therein |
| abstract |
The disclosure provides a method for preparing drug toxin PNU-159682 (morpholinyl anthracycline derivative) for antibody-conjugated drugs and intermediates involved in the preparation method. The preparation method of the present disclosure improves the stability, practicability and scalability of the process by introducing protecting groups and changing to reagents that are capable to amplify; the preparation method of the present disclosure minimizes the risk and operational difficulty during scale-up production; production and operation is simple and convenient. |
| priorityDate |
2019-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |