http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3902793-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_801ef62cfee1c7db5f40bc7cb9ea4391
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-82
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04
filingDate 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adcd75156c4051b37d1829c03fc53ad1
publicationDate 2021-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3902793-A1
titleOfInvention Chemical compound manufacture, new salt form, and therapeutic uses thereof
abstract There is disclosed a method of preparing a compound of Formula (1), or a salt thereof (1) the method comprising: a) treating a compound of Formula (2) sequentially with o-tolylmagnesium chloride, N-methylpiperazine and iodine, under conditions sufficient to obtain a compound of Formula (3) b) treating the compound of Formula (3) from step a) with 3,5-bis(trifluoromethyl)benzyl bromide and a suitable base, under conditions sufficient to obtain a compound of Formula (1).
priorityDate 2018-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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