http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3899957-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4bd24d0edc441a277cf5d128b2c97b31 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B50-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B50-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-20 |
| filingDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f686b6d094a6f32575ccf42a37850e67 |
| publicationDate | 2021-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3899957-A1 |
| titleOfInvention | Systems and methods for estimating cell source fractions using methylation information |
| abstract | Systems and methods are disclosed for determining a cell source fraction in a biological sample of a test subject. Nucleic acid fragments are obtained from a biological sample, comprising cell-free nucleic acid, of the test subject. A methylation state is obtained for each nucleic acid fragment in a first plurality of nucleic acid fragments. Each respective nucleic acid fragment is individually assigned a first score, thereby obtaining a first plurality of scores. Each respective score represents a likelihood that the corresponding nucleic acid fragment was obtained from a cell-free nucleic acid molecule associated with the first cell source. The first plurality of scores is transformed into a first plurality of counts, each count in the first plurality of counts being for a methylation site in a first predetermined set of methylation sites. A first cell source fraction for the test subject is estimated using the first plurality of counts. |
| priorityDate | 2018-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.