| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fef41decf43a526efb071b7ec1c677c2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2da25899011f0af79f7c5f9476f05077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cee985e7bab7bce495912b4829859684
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42f352cc5bd193c17ffff15bf60e16f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cc72748e420bd448cb2e67662725444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1065
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5306 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_152e98804999756ee9d357326e13616a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03360ba4b03c1aedbd41bdd8dd0e27d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cb0625568ab588261a8f804c9163cd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07e18a3a83e26fb5805ca8e529fc24f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fca7e314800a1f65e7679a66edc2123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48a43c00cababa0caea3917de8721f15 |
| publicationDate |
2021-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3899027-A1 |
| titleOfInvention |
Identification of cognate pairs of ligands and receptors |
| abstract |
The invention concerns a method for identifying cognate pairs of a ligand species and a receptor species, comprising co-compartmentalising ligand species and receptor species to form a set of microreactors, each microreactor comprising at least one ligand species and preferably at least one receptor species; assaying the recognition between ligands and receptors in each microreactor and based on this assay, classifying each microreactor as positive when at least one ligand species and at least one receptor species in the microreactor recognize one with the other or negative when no ligand species and no receptor species recognize in the microreactor; identifying ligand species and receptor species contained in each positive microreactor; establishing a subset of positive microreactors containing the same receptor species; determining the probability that in a given subset of positive microreactors containing the same receptor species, the ligand species recognizing the receptor species corresponds to the most frequent co-compartmentalized ligand species; and if the determined probability is greater than a predetermined threshold, identifying as a cognate pair the receptor species and the most frequent co-compartmentalized ligand species. |
| priorityDate |
2018-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |