http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3880689-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_22b4f8ce0ad44b7eff6db8dddf1438dd |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K15-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 |
filingDate | 2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de06d0e8ae1342f7922f4eea847ae881 |
publicationDate | 2021-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-3880689-A1 |
titleOfInvention | Rna preservation solution and methods of manufacture and use |
abstract | Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a buffering agent, a chelating agent, a surfactant, an alcohol, and a reducing agent. Compositions as aqueous solutions can include water as a carrier. Preferred embodiments include RNAse-free water, lithium chloride, sodium citrate, EDTA, CTAB or SLS, SDA 3C, and TCEP, with HCl optionally added to adjust pH. Some embodiments include a colored dye as a visual indicator. Methods of manufacturing include combining the components into a mixture, such as an aqueous solution. Methods of use include providing a biological sample that includes nucleic acid, preferably RNA, and contacting the biological sample with the composition. Kits include a biological sample collection apparatus and the composition. The composition is optionally disposed in a portion of the collection apparatus. |
priorityDate | 2018-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 285.