Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18562 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 |
filingDate |
2013-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f51163f8f5c4200465b7b08adcd9723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd7a97a785c8e92f81360748ef4be31d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7e982e734b8ee06ef46a57ea73ea7cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_650c41fee7fbde702f37e1e3745d3f02 |
publicationDate |
2021-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3875112-A1 |
titleOfInvention |
Genetically stable live attenuated respiratory syncytial virus vaccine and its production |
abstract |
Provided herein are recombinant respiratory syncytial viruses that contain mutations that make the disclosed viruses attractive vaccine candidates. The viruses disclosed contain attenuating mutations designed to have increased genetic and phenotypic stability. Desired combinations of these mutations can be made to achieve desired levels of attenation. Exemplary vaccine candidates are described. Also provided are polynucleotides capable of encoding the described viruses, as wells as methods for producing the viruses and methods of use. |
priorityDate |
2012-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |