abstract |
73 Abstract "Treatment of immune dysregulation disorders" An isolated protease comprising a polypeptide having the structure is described: P-A-B5 in which P is a protease domain, A is an A-domain, and B is a B-domain, of a Group VII to XIII cell envelope protease (CEP), wherein the protease does not have a PA domain. An isolated protease according to Claim 1, selected from a wild-type Group VII to XIII cell envelope protease. The use of the protease as a medicament is treating immune dysregulation diseases is also described.10 (Fig. 8) |