Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_870c6e68c09f6b820fc9b7fefe1a56fc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6881 |
filingDate |
2019-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3753c4811897902d58b79754247411eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_885a8a8cac26e695c8128bc2704c3cfc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc991ba34397a5f92aefb8e6ff5d56aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4614f85b5f185d2ebf0e578b0b9d259 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05b2cdcc521d85844fe9115722433b12 |
publicationDate |
2021-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3856932-A1 |
titleOfInvention |
Methods and uses for determining osteogenic potential of in vitro differentiated cells |
abstract |
The application provides the use of CD73, CD105, CD44 and/or CD10 for determining osteogenic potential of in vitro differentiated cells. The application further provides a method for determining osteogenic potential of in vitro differentiated cells comprising measuring the quantity of the in vitro differentiated cells expressing CD73, CD105, CD10 and/or CD44, and/or measuring the quantity of CD73, CD105 and/or CD44 expressed by the in vitro differentiated cells. The invention also provides a method for selecting a subject for preparing in vitro differentiated cells of chondro-osteoblastic lineage comprising recovering MSC from a biological sample of a subject; obtaining in vitro differentiated cells from the MSC; determining the osteogenic potential of the in vitro differentiated cells by a method as disclosed herein; and selecting the subject for preparing in vitro differentiated cells of chondro-osteoblastic lineage if the in vitro differentiated cells have clinically useful osteogenic potential. |
priorityDate |
2018-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |