| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_53b4d53983adbf56dd0e7d0bf96f8ce5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae364b6226cded09647f2a4e94d4b855 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3625
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3641 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 |
| filingDate |
2019-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ba56d55c0c284584402bafbd89c36f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d74b9d8fb63ef25e8f55378130464a18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6abb940a31ebd1e53103d421d6e43571
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_becbba558030bccb68797d895e001ae8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0968f5bc9be8958ae659d363a61e1d2b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9978b989623bf452444ca092e1ef2c6d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c5d6a251c3ea753f3453e3832f56366 |
| publicationDate |
2021-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3854425-A1 |
| titleOfInvention |
Pre-loadable dried biological heart valve and preparation method thereof |
| abstract |
A pre-loadable dried biological heart valve and a preparation method thereof. The preparation method includes: Step A: soaking a fresh animal pericardium in an aqueous solution of soluble elastin or glycosaminoglycan, and then subjecting the pericardium to a first cross-linking reaction in a mixed solution of carbodiimide or N-hydroxysuccinimide to allow the soluble elastin or glycosaminoglycan to bind to the pericardium via a chemical bond; and Step B: subjecting the pericardium after the first cross-linking to a second cross-linking reaction in an aqueous glutaraldehyde solution, and then drying the pericardium after the second cross-linking, to obtain the pre-loadable dried biological heart valve. The dried biological heart valve obtained by the above preparation method has good toughness, and is rapidly flattened out in a simulated folding and pressing test. |
| priorityDate |
2018-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |