Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d50a5d08fff80f620aa6f328cd9bc85e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ca0841c52dc980c3f201762d410f79b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-155 |
filingDate |
2019-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a42b7452705cd140ee02230811393c54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54882450efed8123dd48a62c5dd5c239 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab52bb5742f7944423d253a870d46259 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c142253d5d3d2974e66269d8f02f94f6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_634132834a36371f0ebba1f15289403d |
publicationDate |
2021-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3837277-A1 |
titleOfInvention |
Recombinant newcastle disease viruses and uses thereof for the prevention of rsv disease or human metapneumovirus disease |
abstract |
Described herein are recombinant Newcastle disease viruses ("NDVs") comprising a packaged genome, wherein the packaged genome comprises a transgene encoding a respiratory syncytial virus ("RSV") F protein or human metapneumovirus ("hMPV") F protein. Also described herein are recombinant NDVs comprising a packaged genome, wherein the packaged genome comprises a transgene encoding a chimeric F protein, wherein the chimeric F protein comprises (i) an RSV F protein ectodomain and NDV F protein transmembrane and cytoplasmic domains; or (ii) an hMPV F protein ectodomain and NDV F protein transmembrane and cytoplasmic domains. The recombinant NDVs and compositions thereof are useful for the immunizing against RSV or hMPV as well as the prevention of RSV disease or hMPV disease. |
priorityDate |
2018-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |