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filingDate 2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40b9db89d6b77ffa77ff56cc45079278
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publicationDate 2021-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3817727-A1
titleOfInvention Method for the production of freeze-dried pellets comprising an anti-coagulation factor xia (fxia) antibody
abstract A method for the production of freeze-dried pellets comprising an anti-FXIa antibody comprises the steps of: a) freezing droplets of a solution comprising an anti-FXIa antibody to form pellets; b) freeze-drying the pellets; wherein in step a) the droplets are formed by means of droplet formation of the solution comprising an anti-FXIa antibody into a cooling tower which has a temperature-controllable inner wall surface and an interior temperature below the freezing temperature of the solution and wherein in step b) the pellets are freeze-dried in a rotating receptacle which is housed inside a vacuum chamber.
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