Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e5c121269689cbab9b3a4548b15caf3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 |
filingDate |
2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cb529ea8e70191106527800a8fc05cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f7d4bbd36e79492bcb7c7b995741132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60f4a0400fb772a2763a13e4f7f54b87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a2f2ea37a5a9d7ffb1eeeb8cc898ded http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa8891684d810bd3a5851d6a6a47bb91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2feccf19232fbbac22cc10b83a9e7975 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e3794b5b1345da67c67a2316de0c4f9 |
publicationDate |
2021-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3816300-A1 |
titleOfInvention |
Conjunctival disease detection method using ocular surface tissue, and biomarker for aging |
abstract |
It aims to construct a technology in which the onset or progression of an aging state or a specific disease can be evaluated in an objective and highly reproducible manner, and in particular, to provide a method of detecting conjunctival diseases such as conjunctival MALT lymphoma, and to provide an aging biomarker that serves as an indicator of the aging state.A method of detecting a conjunctival disease using an ocular surface tissue, the method comprising a step of comparing a microbial community structure of a microbiota included in an ocular surface tissue specimen sampled from a healthy person, with a microbial community structure of a microbiota included in an ocular surface tissue specimen sampled from a subject to detect an ocular surface tissue specimen which is sampled from the subject evaluated as having the conjunctival disease based on a change in the microbial community structure between the healthy person and the subject, and an aging biomarker for detecting an aging state, the aging biomarker comprising a bacterial species which belongs to at least one family selected from Corynebacteriaceae family and Propionibacteriales family in an ocular surface tissue. |
priorityDate |
2018-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |