| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef984517ad4fa88458ab2a9b88ab9961 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-648
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0668
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0654
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-648
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502707 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate |
2019-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba08276ac0019a9505a55b743ea69569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_453302b8f661ed4ae5087d0382cbe4e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dec15f4909df78f52737ded89ae12f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9998176b3ae5fa7d10bc4215b05f1abd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfc4e7dc03dbbf9861001a2fc22b143e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cdb95b56ae6bec857a2af4af9f5d510 |
| publicationDate |
2021-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3811078-A1 |
| titleOfInvention |
A method and device for assaying the interaction and dynamics of permeation of a molecule and a lipid bilayer |
| abstract |
A method of assaying the interaction of a molecule and a lipid bilayer is described. The method employs a microfluidic device comprising a substrate having at least one concave microcavity with a metallic surface defining an aperture and a liquid disposed within the microcavity, a lipid bilayer suspended across the aperture, and a microfluidic channel containing a liquid disposed on top of the substrate in fluid communication with the lipid bilayer. The method comprises the steps of passing a liquid containing a test molecule across the microfluidic channel, and monitoring lipid bilayer molecule interactions by plasmonically enhanced Raman or fluorescence spectroscopy configured for plasmonic enhancement of a detection signal evolving from the test molecule or lipid bilayer. Also described in a microfluidic device configured to perform the method of the invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115096871-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115096871-A |
| priorityDate |
2018-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |