Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_deb5e8a8ddf3e2b19a64314370dc9be6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f146242850b174b114cdb31f58fb922f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-974 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 |
filingDate |
2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01c9092f4a9e4e3c73497bf81d3c3586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4c79128533dcae760f5d6f5ea0e35c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5df19afe6d4146e021de0e0532f7bb7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_474013e9c2a3d0da8285a8a6c2f8c46d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b8487b998b66bd079fbaa49f24bc147 |
publicationDate |
2021-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3808841-A1 |
titleOfInvention |
Method for preparation of thrombin |
abstract |
The present invention is directed to methods for the production of thrombin from a source of prothrombin using a given BaSO<sub>4</sub> reagent as an adsorbent of prothrombin as well as methods for evaluating the suitability of a given BaSO<sub>4</sub> reagent for use in preparation of thrombin. In at least one embodiment, the method includes contacting a sample of the given BaSO<sub>4</sub> reagent with a source of prothrombin to obtain BaSO<sub>4</sub>-adsorbed prothrombin, and subsequently evaluating the pro-coagulant activity of the BaSO<sub>4</sub>-adsorbed prothrombin. In another embodiment, the method includes the step of evaluating relative to the pro-coagulant activity of normal mammalian plasma. |
priorityDate |
2015-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |