| abstract |
The present invention comprises compounds of Formula I. Formula I wherein: R1, R2, R3, R4, R5, Ra, Rb, Q1, and Q2 are defined in the specification. The invention also comprises a method of treating or ameliorating a ROR-ꝩ-t mediated syndrome, disorder or disease, including wherein the syndrome, disorder or disease is selected from the group consisting of rheumatoid arthritis, psoriatic arthritis, and psoriasis. The invention also comprises a method of modulating RORꝩt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I. |