| abstract |
The present invention relates to the use of a substrate comprising a textured surface with a plurality of protrusions and a bulk portion, for promoting neural cell network growth in vitro and/or ex-vivo; for a culturing method; and for complex neural cell network reconstruction. The invention also relates to the use of a substrate for cell stimulation; and to a probe, a stimulation device, and a monitor device comprising the substrate and their uses. In addition, the invention relates to compositions comprising the substrate and their medical uses. Moreover the invention relates to a kit comprising the substrate. |