Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e67739af533921705c6fdeb7b3b25efe |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate |
2019-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a15893e9b77dd1ca78de2c0f2dd7fb75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1c56ef8c0e69653c89d5e8f7b5a6463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc141320c29cd184c8bc78f047842821 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4e68426d97f11505cdbb4bc5ee9fa31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f527c05b372cc1527c228df9d4d1ce35 |
publicationDate |
2021-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3802835-A1 |
titleOfInvention |
Method for generating a gene editing vector with fixed guide rna pairs |
abstract |
The present invention pertains to a novel method for the generation of a vector construct suitable for gene editing applications which comprises a fixed pair of predetermined ex- pressible guide RNA (gRNA) sequences. The method of the invention allows for an easy construction of such vectors and provides in addition thereto vector libraries for the expres- sion of fixed pairs of gRNAs. The vectors of the invention may be advantageously used to cut out larger genomic DNA sequences, or alternatively, to simultaneously introduce muta- tions in the genome without a loss or larger genomic sequences. Hence, the system of the invention provides for many molecular genetic approaches for genome alteration. |
priorityDate |
2018-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |