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filingDate 2019-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3796965-A1
titleOfInvention Balloon catheter
abstract The invention locally delivers a chemotherapeutic or a radiographic contrast agent to an upper tract urothelial carcinoma (UTUC). The invention includes a balloon catheter with a working channel and a balloon placed into the ureter/renal pelvis via retrograde or antegrade ureteral access. The balloon is inflated to temporarily obstruct the ureter, and a formulation with a chemotherapeutic agent is infused into the working channel of the catheter and allowed to dwell in the ureter/renal pelvis for a time sufficient to allow the formulation to adhere to and penetrate the urothelial wall. The formulations can be liposomal or non-liposomal formulations. At least a portion of the infused chemotherapeutic-agent formulation adheres to the urothelial wall while it is instilled and dwells in the ureter/ renal pelvis. The methods of the invention can be performed as an adjuvant therapy to other methods of treating UTUC, including ureteroscopic ablation or resection of the tumor.
priorityDate 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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