| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_11b6b43c7d7f4b33377f6b7a7b4250e6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3181 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-606
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6491 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
| filingDate |
2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04ce3ec28b6d95e2d99d7e3c8c714da9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28185b216db26c934b80b1e4c51f3a2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8066b0e8db6d7c2b21ce0cdf33e32d77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52c522c9efdfd1a4e3dc20e8caad0918
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a683b24334bea89ad864a99e3b1b3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cf0210db4d383b436253eb4b25ecac9 |
| publicationDate |
2021-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3794124-A1 |
| titleOfInvention |
Matrix metalloproteinase-1 antisense oligonucleotides |
| abstract |
A method to treat diseases or conditions associated with the human MMP-1 gene transcription involving administration of the peptide nucleic acid derivative according to claim 1 to a subject. The present invention provides the peptide nucleic acid derivative according to claim 1 which targets 5' splice site of the human MMP-1 pre-mRNA "exon 5". The peptide nucleic acid derivatives in the present invention strongly induce splice variants of the human MMP-1 mRNA in cell and are very useful to treat conditions or diseases of skin aging associated with the human MMP-1 protein. |
| priorityDate |
2018-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |