http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3793621-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c04036bba1a94348a49305ea1aa341e0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0035 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00 |
| filingDate | 2019-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48f766919f617acf7636c218ae47742b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51f874feb0ab2b53eca2a0d658ac1ea6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c458474246c2ceec0926d25614d660e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b14d2360d4f70518f22b72b0a18e9420 |
| publicationDate | 2021-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3793621-A1 |
| titleOfInvention | Protection of biologically active molecules during radiation sterilization |
| abstract | Compositions and methods are disclosed that relate to protecting biological activity of a biologically active molecule, including a biologically active protein or biological response modifier such as an immune response modifier, against radiation damage during radiation sterilization. Inclusion of at least one radioprotectant compound, for example, cysteine, reduced glutathione, melatonin, and/or histidine, in an exemplary mitogenic lectin formulation during spray-drying onto surfaces of immunoassay tubes, surprisingly protected the lectin against loss of biological (mitogenic) activity that would otherwise result from electron beam radiation sterilization. The radioprotectant compound also protected other biologically active molecules and stabilized their biological activities, permitting them to retain biological activity after extended storage following the radiation treatment. |
| priorityDate | 2018-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 146.