| abstract |
The problem of the present invention is to provide a medicament-containing particle having sufficient strength durable against compression, coating and the like, and imparted with desired functionality and a process for preparation thereof and the like.The present invention provides a particle composed of a shell and a hollow, wherein the shell contains a medicament and a polymer, and a volume ratio of the hollow relative to the whole particle is 1% - 50%. The present invention also provides a process for preparation of the above hollow particle, which includes a step of granulating a powder mixture containing a medicament and a polymer, while spraying a solvent capable of dissolving the polymer. |